Effect of Growth Hormone on Plasma Unesterified Fatty Acid Levels of Hypophysectomized Rats

Abstract
Injection of growth hormone into hypophysectomized rats causes a significant rise in concentration of plasma unesterified fatty acids after an 8-hour interval, with no concomitant rise in esterified fatty acids. Injection of inactivated growth hormone does not cause this effect. It is postulated that this rise in unesterified fatty acids may provide an important source of energy for the known protein anabolic effect of growth hormone.