A Novel Form of Mouse Cytochrome P 450 3A (Cyp3a‐16)
Open Access
- 1 December 1994
- journal article
- Published by Wiley in European Journal of Biochemistry
- Vol. 226 (3), 877-882
- https://doi.org/10.1111/j.1432-1033.1994.t01-1-00877.x
Abstract
A complementary DNA clone coding for a novel form of cytochrome P 450, Cyp3a‐16, in mouse fetal livers was isolated and completely sequenced. This clone encoded a polypeptide of 504 deduced amino acids and showed 87.3% and 66.6% amino acid identities with mouse Cyp3a‐11 and Cyp3a‐13, respectively. Cyp3a‐16 transcript was detectable before birth and remarkably diminished five weeks after birth in mice. We conclude that Cyp3a‐16 is a fetal‐ and puberty‐specific cytochrome P 450 in mice.Keywords
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