The history of cholecystography has been reviewed in the literature.1Iodophthalein sodium (Iodeikon), producing a high degree of cholecystographic accuracy, was the first orally given cholecystographic medium to be popularized. In fact, it is doubtful whether the administration of subsequent orally given mediums actually has increased the accuracy of diagnosis for cholecystic disease. The chief objections to iodophthalein sodium were its disagreeable taste and the high incidence of nausea, vomiting, and diarrhea following oral administration. Iodoalphionic acid (Priodax) was tolerated much better and almost universally replaced iodophthalein sodium. Monophen, 2-(4-hydroxy-3,5-diiodobenzyl)-cyclohexane carboxylic acid, although well tolerated and capable of producing equally good cholecystograms, never became popular and is no longer manufactured. Although iodoalphionic acid is employed occasionally, iopanoic acid (Telepaque) and iophenoxic acid (Teridax) are the cholecystographic mediums used most frequently today. It is generally agreed that an ideal orally given cholecystographic medium should produce a gallbladder shadow of sufficient