Molluscan ligand-gated ion-channel receptors
- 1 January 1993
- book chapter
- Published by Springer Nature
- Vol. 63, 48-64
- https://doi.org/10.1007/978-3-0348-7265-2_3
Abstract
In this chapter we introduce the reader to the structures of the different types of ligand-gated ion-channel receptor, and the numerous receptor subtypes that have recently been revealed to exist, in both invertebrate and vertebrate species, by the application of molecular biological methods. We then review some of the data in support of the existence, in molluscs, of such receptor/channel complexes for γ-aminobutyric acid, glutamate and acetylcholine. Finally, recent results from our laboratory on the cloning and expression of complementary DNAs, from the pond-snail Lymnaea stagnalis, that encode GABAA and glutamate receptor subunits will be described.Keywords
This publication has 55 references indexed in Scilit:
- Cloning of a cDNA that encodes an invertebrate glutamate receptor subunitFEBS Letters, 1991
- Molecular Cloning of an Invertebrate Glutamate Receptor Subunit Expressed in Drosophila MuscleScience, 1991
- A novel γ subunit of the GABAA receptor identified using the polymerase chain reactionFEBS Letters, 1991
- Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptorFEBS Letters, 1991
- A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTXNeuron, 1990
- Structure and developmental expression of the Dα2 gene encoding a novel nicotinic acetylcholine receptor protein of Drosophila melanogasterFEBS Letters, 1990
- A Family of AMPA-Selective Glutamate ReceptorsScience, 1990
- The rat β1 -subunit of the GABAA receptor forms a picrotoxin-sensitive anion channel open in the absence of GABAFEBS Letters, 1989
- Ionic mechanisms of the rapid (nicotinic) phase of acetylcholine response in identified Planobarius corneus neuronesBrain Research, 1982
- Aspartate: Distinct Receptors on Aplysia NeuronsScience, 1976