Mesenchymal Cells from the Human Embryonic Palate Are Highly Responsive to Epidermal Growth Factor
- 31 July 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 213 (4507), 563-565
- https://doi.org/10.1126/science.7017936
Abstract
An established line of mesenchymal cells from the human embryonic palate is highly sensitive to the stimulatory effect of epidermal growth factor on growth, labeled thymidine incorporation, and ornithine decarboxylase activity. The results suggest that epidermal growth factor may play a key role in development of various human embryonic and fetal tissues.Keywords
This publication has 19 references indexed in Scilit:
- Correlation of receptors for growth factors on mouse embryonal carcinoma cells with growth in serum-free, hormone-supplemented mediumExperimental Cell Research, 1980
- L-Ornithine Decarboxylase: an Essential Role in Early Mammalian EmbryogenesisScience, 1980
- Sarcoma growth factor (SGF): Specific binding to epidermal growth factor (EGF) membrane receptorsJournal of Cellular Physiology, 1980
- Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431.The Journal of cell biology, 1979
- Prevalence of growth hormone deficiency in children with cleft lip or palateThe Journal of Pediatrics, 1978
- Changes in ornithine decarboxylase activity during matrix-induced cartilage, bone and bone marrow differentiationBiochemical and Biophysical Research Communications, 1978
- Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesisNature, 1978
- Elevated levels of cAMP alters the effect of epidermal growth factor in vitro on programmed cell death in the secondary palatal epitheliumExperimental Cell Research, 1977
- 125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.The Journal of cell biology, 1976
- THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONSAnnals of the New York Academy of Sciences, 1949