Denatured DNA as a direct template for in vitro protein synthesis.
- 1 September 1965
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 54 (3), 880-886
- https://doi.org/10.1073/pnas.54.3.880
Abstract
The activity of some single-stranded DNA in stimulating cell-free protein synthesis previously reported is due to the presence of streptomycin or related antibiotics. The addition of such antibiotics to an in vitro system together with single-stranded DNA greatly enhances the incorporation of labeled amino acids. By using DNA of different base compositions and apurlnic acid, it is shown that the specificity of amino acid incorporation is consistent with established codeword assignments.This publication has 12 references indexed in Scilit:
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