MULTIPLE EMULSIONS. PART II: PROPOSED TECHNIQUE TO OVERCOME UNPLEASANT TASTE OF DRUGS
- 1 January 1983
- journal article
- research article
- Published by Taylor & Francis in Journal of Dispersion Science and Technology
- Vol. 4 (3), 237-252
- https://doi.org/10.1080/01932698308943369
Abstract
Multiple emulsions of water in oil in water (W/O/W) have been used as a novel technique to overcome unpleasant taste of drugs. The drug is dissolved in the inner water phase and is released throughout the oil phase in the presence of synthetic gastric juice Yield of preparation and stability have been studied using various sets of different inner (emulsifier I) and outer (emulsifier II)emulsifiers Combination of anionic-nonionic emulsifiers yielded optimal results: High yield of preparation, high stability and complete release of the drug in synthetic gastric juice.Keywords
This publication has 8 references indexed in Scilit:
- TURBIDITY MEASUREMENTS AS A TECHNIQUE FOR EVALUATION OF WATER-IN-OIL EMULSION STABILITYJournal of Dispersion Science and Technology, 1982
- Some features of breakdown in water-in-oil-in-water multiple emulsionsJournal of Colloid and Interface Science, 1981
- Potential of liquid membranes for drug overdose treatment: In vitro studiesJournal of Pharmaceutical Sciences, 1978
- Electron micrography of water-in-oil-in-water emulsionsJournal of Colloid and Interface Science, 1977
- Viscometric method for estimating the stability of W/O/W-type multiple-phase emulsionsJournal of Colloid and Interface Science, 1977
- An attempt at preparing water-in-oil-in-water multiple-phase emulsionsJournal of Colloid and Interface Science, 1976
- PROCEEDINGS OF THE BRITISH PHARMACOLOGICAL SOCIETYBritish Journal of Pharmacology, 1972
- Use of a Sustained-release Multiple Emulsion to Extend the Period of Radioprotection conferred by CysteamineNature, 1971