An unusual genetic code in nuclear genes of Tetrahymena.
- 1 April 1985
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 82 (8), 2452-2455
- https://doi.org/10.1073/pnas.82.8.2452
Abstract
Two histone H3 genes of T. thermophila were cloned and partially sequenced. The DNA sequences strongly suggest that both genes are active in the vegetatively growing cell. Comparison of the derived amino acid sequences of these 2 genes with the actual sequence of Tetrahymena histone H3 results in the surprising conclusion that TAA codes for glutamine. This represents the 1st demonstration of a coding function for this termination codon of the universal code. This observation has important implications for the evolution of ciliates and of the genetic code.This publication has 24 references indexed in Scilit:
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