Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair
- 1 October 1984
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 160 (1), 288-293
- https://doi.org/10.1128/jb.160.1.288-293.1984
Abstract
The lethal and mutagenic effects of various mutagens on N. gonorrhoeae were investigated. Lethality studies demonstrated that N. gonorrhoeae was relatively sensitive to ethyl methanesulfonate, UV light and methyl methanesulfonate. Although N. gonorrhoeae was readily mutated by ethyl methanesulfonate and N-methyl-N''-nitro-N-nitrosoguanidine for the 3 genetic markers assayed, no increase in the mutation frequency was observed for any of the selective markers after UV irradiation or methyl methanesulfonate treatment. These results suggest that N. gonorrhoeae lacks an error-prone repair mechanism.This publication has 38 references indexed in Scilit:
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