How is the Human Genome Project doing, and what have we learned so far?
- 21 November 1995
- journal article
- review article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 92 (24), 10841-10848
- https://doi.org/10.1073/pnas.92.24.10841
Abstract
In this paper, we describe the accomplishments of the initial phase of the Human Genome Project, with particular attention to the progress made toward achieving the defined goals for constructing genetic and physical maps of the human genome and determining the sequence of human DNA, identifying the complete set of human genes, and analyzing the need for adequate policies for using the information about human genetics in ways that maximize the benefits for individuals and society.Keywords
This publication has 83 references indexed in Scilit:
- Hyping up the letdown geneNature, 1995
- COMMENTARY: So many needles, so much hayHuman Molecular Genetics, 1995
- Assessing Mapping Progress in the Human Genome ProjectScience, 1994
- The 1993–94 Généthon human genetic linkage mapNature Genetics, 1994
- Charcot-Marie-tooth disease: a new paradigm for the mechanism of inherited diseaseTrends in Genetics, 1994
- Integrated human genome–wide maps constructed using the CEPH reference panelNature Genetics, 1994
- Ordered Shotgun Sequencing, a Strategy for Integrated Mapping and Sequencing of YAC ClonesGenomics, 1993
- dbEST — database for “expressed sequence tags”Nature Genetics, 1993
- High Speed Automated DNA Sequencing in Ultrathin Slab GelsNature Biotechnology, 1992
- An oligonucleotide hybridization approach to DNA sequencingFEBS Letters, 1989