The Mechanics of the "L.E." Cell Phenomenon, Studied with a Simplified Test

Abstract
Characteristic Hargraves cells of lupus erythematosus develop when blood from lupus patients is brought in contact with an aggregation of dried, normal leukocytes and incubated for 1-2 hours. For the dried substrate, thick films of leukemic blood or imprints of carcinoma or Hodgkins tissue are satisfactory.