Synthesis of allyltitanium compounds by intramolecular nucleophilic acyl substitution reaction of alka-3,5-dienyl carbonates and their unusual regioselectivity in reaction with aldehydes

Abstract

Treatment of carbonates of alka-3,5-dien-1-ols with (η²-propene)Ti(OPrⁱ)₂ resulted in intramolecular nucleophilic acyl substitution (INAS) reaction to afford allyltitanium compounds containing lactone or ester moieties, which add regiospecifically to aldehydes.