The influence of vasopressin and related peptides on glycogen phosphorylase activity and phosphatidylinositol metabolism in hepatocytes
- 15 February 1979
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 178 (2), 493-496
- https://doi.org/10.1042/bj1780493
Abstract
The relative abilities of 7 vasopressin-like peptides to activate [rat] hepatic glycogen phosphorylase and stimulate phosphate incorporation into phosphatidylinositol were compared. Although the individual peptides differed in their potencies, the concentrations required to stimulate phosphatidylinositol metabolism were always greater (about 10 times) than those needed to activate phosphorylase. The molecular specificity of the hepatic vasopressin receptor and the role of vasopressin-stimulated phosphatidylinositol turnover are discussed.This publication has 18 references indexed in Scilit:
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