Prospective Identification of Biologically Active Structures by Topomer Shape Similarity Searching
- 1 September 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 42 (19), 3919-3933
- https://doi.org/10.1021/jm990159q
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Designing Chemical Libraries for Lead DiscoverySLAS Discovery, 1996
- Bioisosterism as a Molecular Diversity Descriptor: Steric Fields of Single “Topomeric” ConformersJournal of Medicinal Chemistry, 1996
- Use of Structure−Activity Data To Compare Structure-Based Clustering Methods and Descriptors for Use in Compound SelectionJournal of Chemical Information and Computer Sciences, 1996
- Bioisosterism: A Rational Approach in Drug DesignChemical Reviews, 1996
- Neighborhood Behavior: A Useful Concept for Validation of “Molecular Diversity” DescriptorsJournal of Medicinal Chemistry, 1996
- New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)quinoline derivativesJournal of Medicinal Chemistry, 1992
- The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonistMedicinal Research Reviews, 1992
- Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteinsJournal of the American Chemical Society, 1988
- Utilization of operational schemes for analog synthesis in drug designJournal of Medicinal Chemistry, 1972
- Quantitative approach to biochemical structure-activity relationshipsAccounts of Chemical Research, 1969