Abstract
1. In Bufo regularis Reuss moulting is accompanied by an increase in the rate of water uptake through the skin. An increase in urine flow is also observed, starting some time after the rate of water uptake has begun to increase. 2. No increase in rate of water uptake occurs following thyroxine feeding on 4 successive days. 3. The possibility that posterior pituitary activity is responsible for the observed increase in rate of water uptake during moulting is discussed.