IDENTIFICATION OF TUBERCLE-BACILLI

  • 1 January 1979
    • journal article
    • research article
    • Vol. B130 (1), 13-19
Abstract
Initial screening of tubercle baccilli with 2-thiophene carboxylic acid hydrazide (TCH) or 2-furoic acid hydrazide (FAH) separates them into 2 groups. Resistant strains are Mycobacterium tuberculosis. Sensitive strains include M. tuberculosis, M. bovis and BCG which are separated by nitratase and O2 requirement tests. Pyrazinamide sensitivity tests allow M. bovis and M. africanum to be identified. The niacin test is not used. Most M. tuberculosis strains from Europeans are resistant to TCH and FAH and are in phage groups A and B, while most from Asians are sensitive and are in phage group I.