Chemical conversion of thymidine into 5-methyl-2′-deoxycytidine

Abstract

In aqueous ammonia, 5-methyl-4-(1,2,4-triazol-1-yl)-1-(β-D-3,5-di-O-acetyl-2-deoxyribofuranosyl)-pyrimidin-2 (1H)-one, which can be prepared from thymidine, yields 5-methyl-2′-deoxycytidine.