Modified Bases Characterized in Intact DNA by Mass-Analyzed Ion Kinetic Energy Spectrometry
- 23 March 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 203 (4386), 1249-1251
- https://doi.org/10.1126/science.570725
Abstract
Pyrolysis of DNA into a chemical ionization source yields protonated bases and other base-containing ions. Kinetic energy spectra allow the characterization of the bases 5-methylcytosine and 1-methyladenine from underivatized salmon sperm DNA. Isomeric bases are distinguishable with this technique.This publication has 13 references indexed in Scilit:
- Alkaloids in Whole Plant Material: Direct Analysis by Kinetic Energy SpectrometryScience, 1978
- Direct Analysis of Mixtures by Mass SpectrometryAnalytical Chemistry, 1978
- Field ionization mass spectrometry. I—Field desorption spectra of nucleotides—experimental problemsJournal of Mass Spectrometry, 1977
- Sequence analysis of oligodeoxyribonucleotides by mass spectrometry. 1. Dinucleoside monophosphatesBiochemistry, 1977
- ErratumAnalytical Biochemistry, 1977
- Analysis of mixtures by collisional activation spectrometry: Pyrolysis products of deoxyribonucleic acidJournal of Mass Spectrometry, 1976
- Analysis of 5-methylcytosine in DNAAnalytical Biochemistry, 1976
- Pyrolysis mass spectrometric studies on nucleic acidsJournal of Mass Spectrometry, 1974
- Pyrolysis field desorption mass spectrometry of deoxyribonucleic acidAnalytical Chemistry, 1973
- Design and Performance of a Mass-analyzed Ion Kinetic Energy (MIKE) SpectrometerAnalytical Chemistry, 1973