Correlated inhibition of ribosomal RNA synthesis and silver staining by actinomycin D
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 47 (3), 329-333
- https://doi.org/10.1007/bf00321025
Abstract
Preferential inhibition of the synthesis of ribosomal RNA by low doses of actinomycin D was used to investigate the quantitative relationship between the intensity of silver staining of nucleoli and the rate of RNA-synthesis. The two parameters were found to be strongly correlated in human diploid fibroblasts.Keywords
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