Studies on Local Anesthetics. XX. Synthesis of Some alpha-Monoalkylamino-2-methylpropionanilides. A New Useful Local Anesthetic.
- 1 January 1960
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 14 (2), 486-490
- https://doi.org/10.3891/acta.chem.scand.14-0486
Abstract
Five new o-monoalkylamino-2-methylpropionanilides in which the alkyl group is an ethyl, n-propyl, isopropyl, n-butyl or isobutyl group have been synthesised. All 5 compounds possess local anesthetic activity and one of them, the n-propylamino compound ("L67"), had such valuable properties that it was subjected to clinical tests. These showed the new compound to be an effective injection anesthetic.This publication has 2 references indexed in Scilit:
- Studies on Local Anesthetics. XIX. Local Anesthetic Activity of N-(Dialkylaminoalkyl)benzamides. Physicochemical Measurements on N-(Dialkylaminoalkyl)benzamides and Benzoic Acid.Acta Chemica Scandinavica, 1960
- Contributions to the Pharmacology and Toxicology of Xylocaine 1)Acta Pharmacologica et Toxicologica, 1952