In Vitro Demonstration of an Endothelial Proliferative Factor Produced by Neural Cell Lines
- 14 November 1975
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 190 (4215), 682-684
- https://doi.org/10.1126/science.171768
Abstract
Cultured endothelial cells exhibit a six- to tenfold increase in thymidine labeling index in response to a soluble factor elaborated by clonal cell lines of neural origin. This factor, endothelial proliferation factor, appears to be a unique property of tumor cells and may mediate the vascularization of these neoplasms.This publication has 8 references indexed in Scilit:
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