Über die Retraktionsvalenz des Fibringerinnsels und über eine Methode zu ihrer Bestimmung

Abstract

In order to estimate the force of clot retraction a new method was evolved. It is measured by the wt. lifted during retraction. Normally this is 224-588 mg. In thrombocytopenia the wt. is reduced to 28-56 mg. depending on the numbers of platelets. The importance of the force of clot retraction in the process of coagulation is discussed. When the readings obtained are normal, "physiological ligature" by occlusion of the vessel proceeds without disturbance. When readings are low, there is a tendency to bleeding as shown by prolonged bleeding time in thrombocytopenia. The phenomenon of the production of filaments of fibrin leading to retraction is descr.