Fluorescent Antibody Technic for Sero-diagnosis of Schistosomiasis in Humans.

Abstract

The use of fluorescein-abeled antiglobulin as an indicator of cercarial antibody is described. Two-hundred and twenty-seven human sera were tested with this fluorescent antibody technic and the results were compared with those obtained by using the cercarial flocculation test. Sensitivity of the procedure appears to be great for all human schistosome infections. While non-specific staining occurs regularly with sera from trichinosis patients, the specificity with other sera obtained from patients with parasitic, mycotic or degenerative diseases suggests that this procedure may be useful in the serological diagnosis of human schistosomiasis.