A dose‐response study examining the effects of ritanserin on human slow wave sleep.
- 1 February 1991
- journal article
- clinical trial
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 31 (2), 193-196
- https://doi.org/10.1111/j.1365-2125.1991.tb05514.x
Abstract
This study investigated the effects of placebo, 1 mg, 3 mg, 10 mg and 30 mg ritanserin and 10 mg diazepam on human sleep. Twelve normal volunteers participated in this randomized, double‐blind, placebo‐ controlled cross‐over sleep study. A clear dose‐response relationship was found for ritanserin with higher doses evoking increased duration of slow wave sleep.Keywords
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