Human and Mouse Hypoxanthine-Guanine Phosphoribosyltransferase: Dimers and Tetramers
- 12 January 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 203 (4376), 174-176
- https://doi.org/10.1126/science.569362
Abstract
Human and mouse hypoxanthine-guanine phosphoribosyltransferase subunits combine to form an active heteropolymer. Dimers form the basic subunit structure of the enzymes, yet the dimers can readily associate to form tetramers. The equilibrium between dimers and tetramers is significantly influenced by the ionic strength of the enzyme solvent.This publication has 17 references indexed in Scilit:
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