Multiplicity of the Tumor-Directed Immune Response: Implications for Immunotherapy

Abstract
• The host may generate several different types of immune response to a tumor. Some of these responses are advantageous to the host; others are not. There is evidence that several tumor-associated antigens, perhaps stimulating different facets of the immune response, are expressed by the tumor cell. We discuss the implications of this concept for immunotherapy. (Arch Otolaryngol 101:660-663, 1975)