THE ELUTION PROPERTIES OF TYPE 1 POLIOVIRUSES FROM AL(OH) 3 GEL. A POSSIBLE GENETIC ATTRIBUTE
- 1 September 1961
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 47 (9), 1501-1507
- https://doi.org/10.1073/pnas.47.9.1501
Abstract
Virulent type 1 viruses eluted readily from A1(OH)3 gel in the alkaline pH range; attenuated type 1 viruses eluted very poorly under the same conditions. It is postulated that this reflects differences in structure of the protein portion of the virus particle. The standard virulent type 2 (MEF1) and type 3 (Saukett) viruses also tend to elute more readily than the corresponding attenuated P712 and Leon strains, but the differences are not so marked as with type 1 strains.Keywords
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