XLSX file 261K, Supplementary Table S3. Mutations seen in patients with tumors at one time point. For patients with whole exome sequencing data on either pre-treatment (for early resistance cases) or after relapse (for acquired resistance cases), this table summarizes the complete set of non-synonymous mutations and short insertion/deletions called. Alterations in this table met the additional criteria of at least 30X coverage in the tumor and an allelic fraction of at least 0.05. Each column is a patient, each row is a gene, and each non-blank entry denotes the protein change that results from the mutation seen