Bacterial Interference by Oropharyngeal and Clinical Isolates of Anaerobic Bacteria

Abstract

Anaerobic isolates were tested for bacterial inhibitory activity. Of 144 isolates, 102 were from oropharyngeal washings, and 42 were from clinical specimens. Thirteen facultative bacterial species (seven members of the Enterobacteriaceae and six species of gram-positive cocci) were used as indicators of inhibition. Eleven anaerobic species were isolated from oral secretions. All isolates of Bacteroides melaninogenicus, the most commonly recovered species, consistently inhibited several species of indicator bacteria. Bacteroides fragilis, Bacteroides oralis, and Peptostreptococcus anaerobius had unpredictable inhibitory activity, whereas most of the other oral anaerobes were noninhibitory. The 42 clinical species were generally noninhibitory.