Metabolism of Thyroid Hormones by the Isolated Perfused Rabbit Kidney
- 1 January 1977
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 9 (05), 400-403
- https://doi.org/10.1055/s-0028-1093490
Abstract
The metabolism of thyroxine and triiodothyronine in the isolated perfused rabbit kidney was monitored by specific radioimmunoassay for each hormone. The amount of thyroxine catabolised was proportional to the amount added initially and no saturation effects were observed over a wide range (3.9-82 nmol). After addition of thyroxine alone, triiodothyronine could be detected in the perfusion medium within 10 minutes but only much later in the urine. It was proposed that circulating thyroxine contributes indirectly to the level of urinary triiodothyronine.Keywords
This publication has 1 reference indexed in Scilit:
- METABOLISM OF l-THYROXINE BY HUMAN TISSUE SLICES *JCI Insight, 1959