Abstract
A new temperature-sensitive paralytic mutant of Drosophila, comatose [com], is compared behaviorally and physiologically with the previously known types, para [paralyzed] and shi [shibire (paralyzed in Japanese)]. All 3 have different properties with respect to kinetics of paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experiments indicate different mechanisms for paralysis in each of the mutants.