OVARIAN-CARCINOMA - A MULTIVARIATE-ANALYSIS OF PROGNOSTIC FACTORS

Abstract

Women (556) with invasive epithelial ovarian carcinoma were assessed for postoperative treatment between 1966-1976. The records of this group were reviewed retrospectively. Sixteen characteristics of the patient and tumor were analyzed for prognostic significance by univariate and multivariate techniques. Tumor grade, the presence of residual disease and patient performance status were identified as stage-specific independent prognostic factors. These independent factors defined patient subsets with good, intermediate and poor prognosis within each stage. More effective treatment strategies are apparently required for patients in poor prognosis subsets. Estimates of tumor grade, extent of residual disease and performance status should be included in reports of treatment outcome.