Local Injections of Hydrocortisone as a New and Effective Treatment for Strictures of the Urethra and Meatus

Abstract

STRICTURES of the human urethra are of three types: inflammatory, traumatic and congenital. The basic histology¹ common to all strictures is a proliferation of fibroblasts in the tunica propria. This progresses to the point where the elastic tissue and muscle fibers of this area are destroyed and replaced by fibroblasts. In extreme cases the mucosa and corpus spongiosum are also replaced. In inflammatory strictures, the proliferation is accompanied by a marked infiltration of leukocytes. This infiltration takes place to a much less degree in traumatic strictures and is entirely absent in congenital strictures.The clinical course, treatment, complications and prognosis . . .