ENANTIOFACE-DIFFERENTIATING 1,4-ADDITION OF METHYL GRIGNARD REAGENT TO 1,3-DIPHENYL-2-PROPEN-1-ONE
- 5 January 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 9 (1), 45-46
- https://doi.org/10.1246/cl.1980.45
Abstract
A good optical yield (68%) was achieved in the title reaction in the presence of (S)-1-methyl-2-hydroxymethylpyrrolidine as the chiral ligand.Keywords
This publication has 7 references indexed in Scilit:
- Enantioface-differentiating (asymmetric) addition of alkyllithium and dialkylmagnesium to aldehydes by using (2S,2'S)-2-hydroxymethyl-1-[(1-alkylpyrrolidin-2-yl)methyl]pyrrolidines as chiral ligandsJournal of the American Chemical Society, 1979
- Asymmetric Synthesis Based on (2R,3S)-3,4-Dimethyl-2-phenylperhydro-1,4-oxazepine-5,7-dione. Synthesis of Highly Optically Active β-Substituted Alkanoic AcidsBulletin of the Chemical Society of Japan, 1978
- Asymmetric syntheses using tert-leucine. 1. An asymmetric synthesis of .beta.-substituted aldehydes via 1,4-addition of Grignard reagents to chiral .alpha.,.beta.-unsaturated aldiminesJournal of the American Chemical Society, 1976
- The Synthetic Utility of 2‐OxazolinesAngewandte Chemie International Edition in English, 1976
- Oxazolines. XIX. Asymmetric synthesis of 3-substituted alkanoic acids via conjugated addition of organolithium reagents to chiral oxazolinesJournal of the American Chemical Society, 1975
- 1,4-Addition of organometallic reagents to .alpha.,.beta.-unsaturated ketones in the presence of (-)-sparteineThe Journal of Organic Chemistry, 1972
- Studies in stereochemistry. XXXVII. Open-chain models for 1,3-asymmetric induction in stereospecific addition polymerizationJournal of the American Chemical Society, 1968