Enzyme Studies in Muscular Dystrophy. II. Muscle Dipeptidase Activity and Vitamin E-Deficiency.

Abstract
The effect of vit. E-deficiency on hydrolysis of glycylglycine and glycyl-l-leucine by skeletal muscle extracts and homogenates was investigated. During this deficiency there was a marked increase in dipeptidase activity of both muscle extracts and homogenates. The increase in glycylglycine dipeptidase activity could be demonstrated only after the addition of Co++.