The longitudinal sleep electroencephalogram and 24-hour telemetric activity measurements are reported on a patient with a psychotic depression. During the patient's spontaneous partial remission, the sleep patterns showed a marked rapid eye movement recovery, along with other changes in the various sleep parameters. Telemetric activity measurements appeared to mirror certain of the sleep changes so that periods of “hypersomnia” were associated with reduction of activity levels while the periods of insomnia were associated with a marked increase.