Intrapleural Use of Tissue Plasminogen Activator and DNase in Pleural Infection
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- 11 August 2011
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 365 (6), 518-526
- https://doi.org/10.1056/nejmoa1012740
Abstract
More than 30% of patients with pleural infection either die or require surgery. Drainage of infected fluid is key to successful treatment, but intrapleural fibrinolytic therapy did not improve outcomes in an earlier, large, randomized trial.Keywords
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