NMR‐Techniken zum Screening und zur Identifizierung der Bindung von Liganden an Proteinrezeptoren
- 21 February 2003
- journal article
- Published by Wiley in Angewandte Chemie
- Vol. 115 (8), 890-918
- https://doi.org/10.1002/ange.200390202
Abstract
No abstract availableKeywords
This publication has 128 references indexed in Scilit:
- Charakterisierung von Ligandenbindung durch Sättigungstransfer-Differenz-NMR-SpektroskopieAngewandte Chemie, 1999
- NMR-Based Discovery of Lead Inhibitors That Block DNA Binding of the Human Papillomavirus E2 ProteinJournal of Medicinal Chemistry, 1997
- Protein hydration studied with homonuclear 3D1H NMR experimentsJournal of Biomolecular NMR, 1991
- Proton nuclear magnetic resonance studies on the kinetics of tryptic fragments of calmodulin upon calcium bindingBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
- A proton NMR study of the interactions and conformations of rationally designed brodimoprim analogs in complexes with Lactobacillus casei dihydrofolate reductaseJournal of Medicinal Chemistry, 1984
- Theory of the time dependent transferred nuclear Overhauser effect: Applications to structural analysis of ligand-protein complexes in solutionJournal of Magnetic Resonance (1969), 1983
- Proton and fluorine nuclear magnetic resonance spectroscopic observation of hemiacetal formation between N-acyl-p-fluorophenylalaninals and .alpha.-chymotrypsinBiochemistry, 1982
- A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromoleculesBiochemical and Biophysical Research Communications, 1980
- Intermolecular spin diffusion as a method for studying macromolecule-ligand interactionsJournal of Magnetic Resonance (1969), 1979
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973