Genetic counseling in Becker type X‐linked muscular dystrophy. I. Theoretical considerations
- 1 August 1984
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 18 (4), 713-718
- https://doi.org/10.1002/ajmg.1320180417
Abstract
The prior probability of any woman being a carrier for Becker muscular dystrophy (BMD) has been calculated. If μ is the mutation rate in female germ cells and n̈ the mutation rate in male germ cells, this probability is 34/3μ + 20/3v. For all X-linked diseases with a fitness f the prior probability (H) is:Keywords
This publication has 1 reference indexed in Scilit:
- The Application of Bayesian Methods in Genetic CounsellingHuman Heredity, 1969