Resolution, reconstitution and kinetics of the primary action of a hormone receptor
- 1 September 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 287 (5780), 297-300
- https://doi.org/10.1038/287297a0
Abstract
The .beta.-adrenergic receptor (R) and GTP binding protein (G) with which the receptor interacts were obtained in separate soluble fractions. Their recombination produced a hormone [isoprenaline] responsive system. In the presence of hormone the encounter of R with G in the reconstituted membrane of turkey erythrocytes occurs much faster than the subsequent R-induced activation of G.This publication has 38 references indexed in Scilit:
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