ASSAY OF ANTIDIURETIC SUBSTANCE IN PLASMA OF NORMAL AND DIABETES INSIPIDUS DOGS1
- 1 October 1956
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 59 (4), 493-494
- https://doi.org/10.1210/endo-59-4-493
Abstract
Alcohol anesthetized rats constitute a satisfactory and sensitive test for circulating antidiuretic substance in dog plasma. Normal dog plasma contains circulating antidiuretic activity which ranges from 45 to 105 microunit equivalents of vasopressin with a mean of 80 microunit equivalents per cc. Plasma from diabetes insipidus dogs maintained in this condition for a year and a half does not contain any detectable antidiuretic activity.Keywords
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