Formation of 8‐nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination
Open Access
- 4 December 1995
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 376 (3), 207-210
- https://doi.org/10.1016/0014-5793(95)01281-6
Abstract
Peroxynitrite is a strong oxidant formed by reaction of nitric oxide with superoxide in inflamed tissues. We have demonstrated that 8‐nitroguanine is formed dose‐dependently in calf thymus DNA incuba...Keywords
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