New rifamycins modified at positions 3 and 4. Synthesis, structure and biological evaluation.
- 1 January 1981
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 34 (8), 1033-1038
- https://doi.org/10.7164/antibiotics.34.1033
Abstract
A number of semisynthetic rifamycin derivatives modified at positions 3 and/or 4, belonging to general structures 3, 5 and 6 was prepared. The synthesis, structure and antimicrobial evaluation of the new compounds are described. All the derivatives have in vitro antibacterial activities comparable with that of rifampicin.This publication has 1 reference indexed in Scilit:
- Biological activity of a new class of rifamycins Spiro-piperidyl-rifamycins.The Journal of Antibiotics, 1980