What is evidence?
- 29 July 2010
- journal article
- editorial
- Published by Wiley in Statistics in Medicine
- Vol. 29 (19), 1985-1988
- https://doi.org/10.1002/sim.3933
Abstract
The assumption that comparative effectiveness research will provide timely, relevant evidence rests on changing the current framework for assembling evidence. In this commentary, we provide the background of how coverage decisions for new medical technologies are currently made in the United States. We focus on the statistical issues regarding how to use the ensemble of information for inferring comparative effectiveness. It is clear a paradigm shift in how clinical information is integrated in real‐world settings to establish effectiveness is required. Copyright © 2010 John Wiley & Sons, Ltd.Keywords
Funding Information
- National Institute of Mental Health (R01-MH54693)
This publication has 9 references indexed in Scilit:
- Correlated bivariate continuous and binary outcomes: Issues and applicationsStatistics in Medicine, 2009
- Medicare’s National Coverage Decisions For Technologies, 1999–2007Health Affairs, 2008
- Participation in Cancer Clinical TrialsJAMA, 2004
- Network meta‐analysis for indirect treatment comparisonsStatistics in Medicine, 2002
- On the bias produced by quality scores in meta-analysis, and a hierarchical view of proposed solutionsBiostatistics, 2001
- Representation of Elderly Persons and Women in Published Randomized Trials of Acute Coronary SyndromesJAMA, 2001
- The Hazards of Scoring the Quality of Clinical Trials for Meta-analysisJAMA, 1999
- Toward Evidence-Based Medical Statistics. 2: The Bayes FactorAnnals of Internal Medicine, 1999
- A Meta-analysis of 16 Randomized Controlled Trials to Evaluate Computer-Based Clinical Reminder Systems for Preventive Care in the Ambulatory SettingJournal of the American Medical Informatics Association, 1996