Natural Product Synthesis and Vitamin B 12
- 24 June 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 196 (4297), 1410-1420
- https://doi.org/10.1126/science.867037
Abstract
The total synthesis of vitamin B12, through the combined efforts of 2 research groups, provided a framework for exploration in several areas of organic chemistry. This article reviews the problems encountered and the solutions arrived at in the total synthesis of cobyric acid and vitamin B12.This publication has 45 references indexed in Scilit:
- The Artificial Gene: It's Synthesized and It Works in CellsScience, 1976
- Studies on the synthesis of vitamin B12. 1. Introduction and model studiesJournal of the American Chemical Society, 1976
- Nitroso compounds and azo dioxides as quenchers of singlet oxygen (1.DELTA.g) and sensitizer triplet statesJournal of the American Chemical Society, 1976
- Variante des Sulfidkontraktionsverfahrens beim Aufbau corrinoider SystemeAngewandte Chemie, 1973
- Synthesen von Verbindungen der Corrin-Reihe, II1) Umsetzung von Tetradehydrocorrin-Metallkomplexen mit Osmiumtetroxid und FolgereaktionenEuropean Journal of Organic Chemistry, 1970
- Ein neuer synthetischer Zugang zum CorrinsystemAngewandte Chemie, 1969
- A Synthetic Route to the Corrin SystemAngewandte Chemie International Edition in English, 1964
- Solid Phase Peptide Synthesis. I. The Synthesis of a TetrapeptideJournal of the American Chemical Society, 1963
- THE TOTAL SYNTHESIS OF CHLOROPHYLLJournal of the American Chemical Society, 1960
- Synthese des Hämatoporphyrins, Protoporphyrins und HäminsEuropean Journal of Organic Chemistry, 1929