Calcium Metabolism in Tumors: Its Relationship with Chromium Complex Accumulation. I. Uptake of Calcium and Phosphorus by Experimental Tumors

Abstract

The uptake of radiocalcium (⁴⁵Ca) and radiophosphorus (³²P) by 5 different types of experimental tumors have been studied. Through a chemical fractionation various fractions were obtained. Calcium is in corporated mainly in the acetic acid soluble fraction, while phosphorus in the HCl soluble fraction. The tumor necrosis shifts the calcium accumulation to the HCl soluble fraction. These findings indicated that the insoluble calcium is in a chemical form other than hydroxyapatite.