The proximal negative response and visual adaptation in the skate retina.
Open Access
- 31 December 1976
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 69 (1), 57-74
- https://doi.org/10.1085/jgp.69.1.57
Abstract
The proximal negative response (PNR), a complex extracellular potential derived mainly from amacrine cell activity, was studied in the all-rod retina of the skate [Raja erinacea or R. oscellata]. Tetrodotoxin (10-6 mg/ml) did not affect either the waveform or the latency of the response, indicating that the PNR reflects the graded, nonregenerative components of the amacrine cell potential. As regards its adaptive properties, the PNR exhibited both the extreme sensitivity to weak background light and the slow time course of light and dark adaptation that are characteristic of other responses from the proximal retina. The PNR, like the b-wave and ganglion cell discharge, appears to reflect adaptive processes located within the neural network of the inner retina.This publication has 29 references indexed in Scilit:
- Synaptic organization and ionic basis of on and off channels in mudpuppy retina. III. A model of ganglion cell receptive field organization based on chloride-free experiments.The Journal of general physiology, 1976
- Potassium and retinal sensitivityBrain Research, 1976
- Retinal mechanisms of visual adaptation in the skate.The Journal of general physiology, 1975
- Extracellular potassium activity during epileptogenesisExperimental Neurology, 1974
- Tetrodotoxin resistant electrically excitable responses of receptor cellsBrain Research, 1973
- The proximal negative response of the primate retinaVision Research, 1973
- Intensity Coding in the Frog RetinaThe Journal of general physiology, 1973
- Adaptation in Skate PhotoreceptorsThe Journal of general physiology, 1972
- Potassium-selective microelectrodes used for measuring the extracellular brain potassium during spreading depression and anoxic depolarization in ratsBrain Research, 1972
- Organization of the retina of the mudpuppy, Necturus maculosus. II. Intracellular recording.Journal of Neurophysiology, 1969