The Antigenicity of the Rho (Du) Blood Factor
Open Access
- 31 July 1962
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 20 (2), 196-202
- https://doi.org/10.1182/blood.v20.2.196.196
Abstract
The antigenicity of the Rh variant Rho(Du) was investigated by the transfusion of 45 Rh negative (cde/cde) patients with 68 units of "low grade" Rho (Du) blood of the phenotypes Rho(ccDuee) or Rh2(ccDuE). The donor red cells had normal viability; none of the patients made antibodies to Rho(D) or Rho(Du). The results indicate that the inherited, "low grade" Rho(Du) factor is far less antigenic than Rho(D). It was also less antigenic than Kell or rh'' (E) in this study. It remains possible that this variant will prove to be antigenic in some recipients, but the hazard from this is undoubtedly much less than has been expected.This publication has 5 references indexed in Scilit:
- Febrile, Nonhemolytic Transfusion Reactions and the Limited Role of Leukoagglutinins in Their EtiologyTransfusion, 1962
- Severe Haemolytic Transfusion Reactions caused by apparently compatible Red CellsBritish Journal of Haematology, 1961
- AN INTERACTION BETWEEN ALLELES AT THE RH LOCUS IN MAN WHICH WEAKENS THE REACTIVITY OF THE RH 0 FACTOR (D u )Proceedings of the National Academy of Sciences, 1955
- Weakly Reacting Rh Positive (Du) BloodsBlood, 1951
- A New Rh AllelomorphNature, 1946