Nortriptyline and Cognitive-Behavioral Therapy in the Treatment of Cigarette Smoking

Abstract
THE LINK between cigarette smoking and depressed mood is well established in population studies.1-4 There is also evidence that diagnosable depression, particularly major depressive disorder (MDD), and a diagnosis of nicotine dependence are correlated in the general population.5 Individuals with current or historical depressive disorders seem to be overrepresented among those seeking smoking treatment.6,7 Smokers with a history of MDD may experience more severe mood-related symptoms when they quit smoking.8,9