Thymus Cells in Myasthenia Gravis Selectively Enhance Production of Anti-Acetylcholine-Receptor Antibody by Autologous Blood Lymphocytes
- 26 November 1981
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 305 (22), 1313-1318
- https://doi.org/10.1056/nejm198111263052203
Abstract
We investigated the role of the thymus in 16 patients with myasthenia gravis without thymoma by studying the production of anti-acetylcholine-receptor antibody by thymic and blood lymphocytes cultured alone or together. In 10 responders (with the highest receptor-antibody titers in their plasma), cultured thymic cells spontaneously produced measurable receptor antibody.Keywords
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